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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
31.21
Human Site:
S1279
Identified Species:
49.05
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S1279
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S1279
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Dog
Lupus familis
XP_531814
1283
145094
C1217
Y
K
F
I
K
G
A
C
P
K
S
Y
G
F
N
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
S1277
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Rat
Rattus norvegicus
XP_002726765
1361
151628
S1280
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1385
E
N
E
S
E
D
P
S
Q
E
T
I
T
F
L
Frog
Xenopus laevis
NP_001089247
1340
149481
S1261
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
S1288
E
N
E
C
E
D
P
S
Q
E
T
I
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
A1126
P
K
S
Y
G
F
N
A
A
K
L
A
G
M
P
Honey Bee
Apis mellifera
XP_392346
1120
127429
Y1056
Q
E
T
V
T
F
L
Y
K
L
S
E
G
A
C
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
I1122
L
Y
E
L
E
S
G
I
C
P
K
S
Y
G
F
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
S1256
N
E
N
E
E
D
P
S
Q
E
T
I
T
F
L
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
A1220
D
S
I
L
H
N
A
A
A
K
S
R
E
F
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
G1226
Q
I
G
E
G
I
G
G
V
E
E
V
T
F
L
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
L1178
R
L
V
K
E
R
D
L
A
A
N
N
L
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
100
100
N.A.
0
0
13.3
73.3
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
100
N.A.
N.A.
93.3
100
100
N.A.
13.3
20
13.3
73.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
14
20
7
0
7
0
7
0
% A
% Cys:
0
0
0
40
0
0
0
7
7
0
0
0
0
0
7
% C
% Asp:
7
0
0
0
0
54
7
0
0
0
0
0
0
0
0
% D
% Glu:
47
14
54
14
67
0
0
0
0
60
7
7
7
0
7
% E
% Phe:
0
0
7
0
0
14
0
0
0
0
0
0
0
74
7
% F
% Gly:
0
0
7
0
14
7
14
7
0
0
0
0
20
7
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
0
7
0
7
0
0
0
54
0
0
0
% I
% Lys:
0
14
0
7
7
0
0
0
7
20
7
0
0
0
0
% K
% Leu:
7
7
0
14
0
0
7
7
0
7
7
0
7
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
47
7
0
0
7
7
0
0
0
7
7
0
7
7
% N
% Pro:
7
0
0
0
0
0
54
0
7
7
0
0
0
0
7
% P
% Gln:
14
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
7
7
7
0
7
0
54
0
0
20
7
0
0
0
% S
% Thr:
0
0
7
0
7
0
0
0
0
0
54
0
60
0
0
% T
% Val:
0
0
7
7
0
0
0
0
7
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
7
0
0
0
7
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _